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RUNX1 抗体 (C-Term)

This anti-RUNX1 antibody is a 兔 多克隆 antibody detecting RUNX1 in WB 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN3032498
发货至: 中国

Quick Overview for RUNX1 抗体 (C-Term) (ABIN3032498)

抗原

See all RUNX1 抗体
RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))

适用

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人, 小鼠

宿主

  • 144
  • 17
  • 2
  • 1

克隆类型

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  • 20
多克隆

标记

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This RUNX1 antibody is un-conjugated

应用范围

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  • 1
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Western Blotting (WB), ELISA
  • 抗原表位

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    • 1
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    • 1
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    • 1
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    • 1
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    C-Term

    纯化方法

    Antigen affinity purified

    免疫原

    This Runx1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 426-459 amino acids from the C-terminal region of mouse Runx1.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the Runx1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the Runx1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))

    别名

    Runx1

    背景

    CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. Essential for the development of normal hematopoiesis. Isoform 4 shows higher binding activities for target genes and binds TCR-beta-E2 and RAG-1 target site with threefold higher affinity than other isoforms. It is less effective in the context of neutrophil terminal differentiation. Acts synergistically with ELF4 to transactivate the IL-3 promoter and with ELF2 to transactivate the BLK promoter. Inhibits KAT6B- dependent transcriptional activation (By similarity).

    UniProt

    Q03347
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