RPS6 抗体 (AA 220-249)
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北京 101111
Quick Overview for RPS6 抗体 (AA 220-249) (ABIN3032477)
抗原
See all RPS6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 220-249
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交叉反应 (详细)
- Expected species reactivity: Mouse, Rat, Bovine, Primate, Chicken, Xenopus
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 220-249 from the human protein was used as the immunogen for this RPS6 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the RPS6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the RPS6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- RPS6 (Ribosomal Protein S6 (RPS6))
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别名
- RPS6
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背景
- Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
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UniProt
- P62753
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途径
- Carbohydrate Homeostasis, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
抗原
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