PRDM2 抗体 (AA 1-347)
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Quick Overview for PRDM2 抗体 (AA 1-347) (ABIN3032300)
抗原
See all PRDM2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-347
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纯化方法
- Purified
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免疫原
- Purified recombinant GST fusion protein encoding aa 1-347 of human RIZ1. This RIZ1 antibody is specific and does not recognize the beta isoform (RIZ2).
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亚型
- IgG1
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应用备注
- Titration of the RIZ1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,ChIP: 1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the RIZ1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- PRDM2 (PR Domain Containing 2, with ZNF Domain (PRDM2))
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别名
- RIZ1
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背景
- This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.
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UniProt
- Q13029
抗原
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