PRDM2
(PR Domain Containing 2, with ZNF Domain (PRDM2))
适用
人, 小鼠
宿主
小鼠
克隆类型
单克隆
标记
This PRDM2 antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA, Chromatin Immunoprecipitation (ChIP)
克隆位点
33AT1045
抗原表位
AA 1-347
纯化方法
Purified
免疫原
Purified recombinant GST fusion protein encoding aa 1-347 of human RIZ1. This RIZ1 antibody is specific and does not recognize the beta isoform (RIZ2).
Titration of the RIZ1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,ChIP: 1:100
限制
仅限研究用
状态
Liquid
缓冲液
In 1X PBS pH 7.4 with 0.09 % sodium azide
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Aliquot the RIZ1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
抗原
PRDM2
(PR Domain Containing 2, with ZNF Domain (PRDM2))
别名
RIZ1
背景
This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.