Recoverin 抗体 (AA 169-200)
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Quick Overview for Recoverin 抗体 (AA 169-200) (ABIN3032452)
抗原
See all Recoverin (RCVRN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 169-200
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纯化方法
- Purified
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免疫原
- A portion of amino acids 169-200 from the human protein was used as the immunogen for this Recoverin antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the Recoverin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Recoverin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Recoverin (RCVRN)
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别名
- Recoverin
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背景
- Recoverin belongs to a high-affinity calcium-binding family that includes neuronal calcium sensor-1, visinin-like proteins (VILIPs), guanylate cyclase-activating proteins (GCAPs), and Kv-channel interacting proteins (KchIPs). Features common to this family include four calcium-binding EF-hand domains, and an N-terminal myristoylation sequence. This family of proteins has been implicated in a broad range of cellular signaling functions, including phototransduction and neurotransmitter release, lipid metabolism, gene expression, and ion channel regulation. Myristoylation, the post-translational addition of a fatty acid tail, has been shown to have functional significance for other calcium-binding protein family members. Recoverin is subject to the posttranslational modification of myristoylation. Binding of calcium to recoverin elicits a change in conformation that exposes the buried hydrophobic myristoyl moiety to interaction with cell membranes and other cellular proteins.
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UniProt
- P35243
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
抗原
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