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PROX1 抗体 (AA 492-522)

This 兔 多克隆 anti-PROX1 antibody specifically detects PROX1 in WB, ELISA 和 IF. The antibody is reactive with 人 和 大鼠 samples.
产品编号 ABIN3032348
发货至: 中国
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Quick Overview for PROX1 抗体 (AA 492-522) (ABIN3032348)

抗原

See all PROX1 抗体
PROX1 (Prospero Homeobox 1 (PROX1))

适用

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人, 大鼠

宿主

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克隆类型

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多克隆

标记

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This PROX1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 492-522

    交叉反应 (详细)

    Expected species reactivity: Mouse

    纯化方法

    Purified

    免疫原

    A portion of amino acids 492-522 from the human protein was used as the immunogen for this PROX1 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the PROX1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:500,Immunofluorescence: 1:10-1:50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the PROX1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    PROX1 (Prospero Homeobox 1 (PROX1))

    别名

    PROX1

    背景

    The expression pattern of Prox1 suggests that it has a role in a variety of embryonic tissues, including lens. Prox mRNA is present in many different human tissues with lens demonstrating the highest level. Homozygous Prox1-null mice die at midgestation from multiple developmental defects, and a targeted effect on lens development has been reported. Prox1 inactivation caused abnormal cellular proliferation, downregulated expression of the cell cycle inhibitors Cdkn1b and Cdkn1c, misexpression of E-cadherin, and excessive apoptosis. Consequently, mutant lens cells failed to polarize and elongate properly, resulting in a hollow lens.

    UniProt

    Q92786

    途径

    Stem Cell Maintenance, Regulation of Muscle Cell Differentiation
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