CARM1 抗体 (AA 346-377)
Our Local Distributor
北京 101111
Quick Overview for CARM1 抗体 (AA 346-377) (ABIN3030540)
抗原
See all CARM1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 346-377
-
交叉反应 (详细)
- Expected species reactivity: Mouse, Rat
-
纯化方法
- Antigen affinity purified
-
免疫原
- A portion of amino acids 346-377 from the human protein was used as the immunogen for this PRMT4 antibody.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- Titration of the PRMT4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the PRMT4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- CARM1 (Coactivator-Associated Arginine Methyltransferase 1 (CARM1))
-
别名
- PRMT4
-
背景
- Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in signal transduction, metabolism of nascent pre-RNA, and transcriptional activation (Frankel et al., 2002 [PubMed 11724789]).
-
UniProt
- Q86X55
-
途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of fat Cell Differentiation
抗原
-