PFKFB3 抗体 (AA 454-484)
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Quick Overview for PFKFB3 抗体 (AA 454-484) (ABIN3029823)
抗原
See all PFKFB3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 454-484
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交叉反应 (详细)
- Expected species reactivity: Rat
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纯化方法
- Purified
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免疫原
- A portion of amino acids 454-484 from the human protein was used as the immunogen for this PFKFB3 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the PFKFB3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the PFKFB3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- PFKFB3 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3))
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别名
- PFKFB3
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背景
- Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA & PKG) family, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the related to PKA and PKC (RAC/Akt) protein kinase family, the kinases that phosphorylate G protein-coupled receptors family (ARK), and the kinases that phosphorylate ribosomal protein S6 family (RSK).
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UniProt
- Q16875
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途径
- AMPK Signaling, Regulation of Carbohydrate Metabolic Process
抗原
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