Titration of the PDK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
限制
仅限研究用
状态
Liquid
缓冲液
In 1X PBS, pH 7.4, with 0.09 % sodium azide
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Aliquot the PDK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
抗原
PDPK1
(3-phosphoinositide Dependent Protein Kinase-1 (PDPK1))
别名
PDK1
背景
Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation.