PAX5 抗体 (AA 178-207)
Our Local Distributor
北京 101111
Quick Overview for PAX5 抗体 (AA 178-207) (ABIN3032126)
抗原
See all PAX5 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 178-207
-
交叉反应 （详细）
- Expected species reactivity: Mouse
-
纯化方法
- Antigen affinity purified
-
免疫原
- A portion of amino acids 178-207 from the human protein was used as the immunogen for this PAX5 antibody.
-
亚型
- Ig Fraction
-
-
anti-Paired Box 5 (PAX5) (AA 192-301) antibody
PAX5 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 8F9 unconjugated
anti-Paired Box 5 (PAX5) (AA 235-382) antibodyPAX5 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal PAX5-3735 unconjugated
anti-Paired Box 5 (PAX5) (AA 235-382) antibodyPAX5 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 7D3 unconjugated
anti-Paired Box 5 (PAX5) (N-Term) antibodyVerified PAX5 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Paired Box 5 (PAX5) (AA 235-382) antibodyPAX5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A7 unconjugated
anti-Paired Box 5 (PAX5) (AA 217-282) antibodyPAX5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 5 (PAX5) (AA 362-391) antibodyPAX5 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 5 (PAX5) (N-Term) antibodyPAX5 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 5 (PAX5) (AA 192-302) antibodyPAX5 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 8F9 unconjugated
anti-Paired Box 5 (PAX5) antibodyPAX5 适用: 人 WB, ELISA, Coat 宿主: 小鼠 Monoclonal rPAX5-2060 unconjugated Recombinant Antibody
-
-
应用备注
- Titration of the PAX5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50,IHC (Paraffin): 1:10-1:50
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the PAX5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- PAX5 (Paired Box 5 (PAX5))
-
别名
- PAX5
-
背景
- This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9,14)(p13,q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternatively spliced transcript variants encoding different isoforms have been described but their biological validity has not been determined.
-
UniProt
- Q02548
抗原
-
