PAK6 抗体 (AA 116-146)
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北京 101111
Quick Overview for PAK6 抗体 (AA 116-146) (ABIN3032122)
抗原
See all PAK6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 116-146
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纯化方法
- Purified
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免疫原
- A portion of amino acids 116-146 from the human protein was used as the immunogen for this PAK6 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the PAK6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the PAK6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- PAK6 (P21-Activated Kinase 6 (PAK6))
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别名
- PAK6
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背景
- The PAK6 protein shares a high degree of sequence similarity with p21-activated kinase (PAK) family members. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. PAK6 was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. The p21-activated protein kinase 6 gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen.
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UniProt
- Q9NQU5
抗原
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