NRF1 抗体 (AA 226-255)
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Quick Overview for NRF1 抗体 (AA 226-255) (ABIN3032068)
抗原
See all NRF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 226-255
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交叉反应 (详细)
- Expected species reactivity: Mouse, Zebrafish
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 226-255 from the human protein was used as the immunogen for this NRF1 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the NRF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the NRF1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- NRF1 (Nuclear Respiratory Factor 1 (NRF1))
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别名
- NRF1
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背景
- This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternate transcriptional splice variants, which encode the same protein, have been characterized. Additional variants encoding different protein isoforms have been described but they have not been fully characterized. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for 'nuclear factor (erythroid-derived 2)-like 1' which has an official symbol of NFE2L1.
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UniProt
- Q16656
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途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
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