NLRP4 抗体 (AA 121-149)
This anti-NLRP4 antibody is a 兔 多克隆 antibody detecting NLRP4 in ELISA 和 WB. Suitable for 人.
产品编号 ABIN3032022
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Beijing Economic Technological Development Area
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Quick Overview for NLRP4 抗体 (AA 121-149) (ABIN3032022)
抗原
See all NLRP4 抗体
NLRP4
(NLR Family, Pyrin Domain Containing 4 (NLRP4))
适用
人
宿主
兔
克隆类型
多克隆
标记
This NLRP4 antibody is un-conjugated
应用范围
ELISA, Western Blotting (WB)
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抗原表位
- AA 121-149
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 121-149 from the human protein was used as the immunogen for this NLRP4 antibody.
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亚型
- Ig Fraction
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anti-NLR Family, Pyrin Domain Containing 4 (NLRP4) (AA 351-450) antibody
NLRP4 适用: 人, 大鼠 ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Titration of the NLRP4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the NLRP4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- NLRP4 (NLR Family, Pyrin Domain Containing 4 (NLRP4))
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别名
- NLRP4
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背景
- NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP4, have an N-terminal pyrin (MEFV, MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1, MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).
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UniProt
- Q96MN2
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途径
- Inflammasome
抗原
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