NLRP10 抗体 (AA 466-494)
Our Local Distributor
北京 101111
Quick Overview for NLRP10 抗体 (AA 466-494) (ABIN3032014)
抗原
See all NLRP10 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 466-494
-
纯化方法
- Antigen affinity purified
-
免疫原
- A portion of amino acids 466-494 from the human protein was used as the immunogen for this NLRP10 antibody.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- Titration of the NLRP10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the NLRP10 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))
-
别名
- NLRP10
-
背景
- Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis. [provided by RefSeq].
-
UniProt
- Q86W26
-
途径
- Inflammasome
抗原
-