NCAPH2 抗体 (AA 198-227)
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Quick Overview for NCAPH2 抗体 (AA 198-227) (ABIN3032026)
抗原
See all NCAPH2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 198-227
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纯化方法
- Purified
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免疫原
- A portion of amino acids 198-227 from the human protein was used as the immunogen for this NCAPH2 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the NCAPH2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the NCAPH2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- NCAPH2 (Non-SMC Condensin II Complex, Subunit H2 (NCAPH2))
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别名
- NCAPH2
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背景
- Structural maintenance of chromosomes (SMC) and non-SMC condensin proteins associate into complexes that have been implicated in the process of chromosome condensation. A crucial prerequisite for accurate segregation of replicated sister chromatids is the condensation of the chromosomes into a manageable form prior to metaphase. The condensin I complex consists of two SMC subunits, SMC2 and SMC4, and three non-SMC subunits, CAP-H, CAP-G, and CAP-D2. An alternative complex, the condensin II complex, contains alternate non-SMC subunits, CAP-G2, CAP-H2, and CAP-D3. CAP-H2 is also known as Non-SMC condensin II complex, subunit H2 (NCAPH2) or kleisin beta isoform 2. The three non-SMC subunits in the condensing complexes form a regulatory subcomplex that is required to activate the SMC ATPases and to promote mitosis-specific chromatin binding of the holocomplex. The precise individual functions of each non-SMC protein in activation remain to be determined.
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UniProt
- Q6IBW4
抗原
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