Metabotropic Glutamate Receptor 5 抗体 (AA 1020-1050)
Quick Overview for Metabotropic Glutamate Receptor 5 抗体 (AA 1020-1050) (ABIN3031075)
抗原
See all Metabotropic Glutamate Receptor 5 (GRM5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1020-1050
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纯化方法
- Purified
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免疫原
- A portion of amino acids 1020-1050 from the human protein was used as the immunogen for this mGLUR5 antibody.
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亚型
- Ig Fraction
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anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 458-580) antibody
GRM5 适用: 人 IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 1A11D10 unconjugated
anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 367-380), (Extracellular) antibodyGRM5 适用: 大鼠 WB, IHC, IF, FACS, IC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 419-518) antibodyGRM5 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1B3 unconjugated
anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 824-1203) antibodyGRM5 适用: 大鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S75-33 unconjugated
anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 824-1203) antibodyGRM5 适用: 大鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S75-3 unconjugated
anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 824-1203) antibody (HRP)GRM5 适用: 大鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S75-3 HRP
anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 824-1203) antibody (HRP)GRM5 适用: 大鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S75-33 HRP
anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 824-1203) antibody (FITC)GRM5 适用: 大鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S75-3 FITC
anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 824-1203) antibody (FITC)GRM5 适用: 大鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S75-33 FITC
anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 824-1203) antibody (Biotin)GRM5 适用: 大鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S75-3 Biotin
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应用备注
- Titration of the mGLUR5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the mGLUR5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))
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别名
- mGLUR5
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背景
- L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 (also known as GPRC1E) and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. The activity of GRM5 is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current.
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UniProt
- P41594
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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