MCM8 抗体 (AA 322-350)
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Quick Overview for MCM8 抗体 (AA 322-350) (ABIN3031814)
抗原
See all MCM8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 322-350
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 322-350 from the human protein was used as the immunogen for this MCM8 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the MCM8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the MCM8 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))
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别名
- MCM8
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背景
- The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described.
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UniProt
- Q9UJA3
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途径
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
抗原
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