MAVS 抗体 (AA 477-505)
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北京 101111
Quick Overview for MAVS 抗体 (AA 477-505) (ABIN3031816)
抗原
See all MAVS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 477-505
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 477-505 from the human protein was used as the immunogen for this MAVS antibody.
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亚型
- Ig Fraction
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anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 1-65) antibody
MAVS 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 34-96) antibodyMAVS 适用: 人 WB, IHC, ICC, IHC (fro), FACS 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (C-Term) antibodyMAVS 适用: 人, 小鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 1-540) antibodyMAVS 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 160-450) antibodyMAVS 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal Adri-1 unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (N-Term) antibodyMAVS 适用: 人, 小鼠, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 470-519) antibodyMAVS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 146-195) antibodyMAVS 适用: 人, 小鼠, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 1-30), (N-Term) antibodyMAVS 适用: 小鼠 WB 宿主: 兔 Polyclonal RB42373 unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 1-30) antibodyMAVS 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Titration of the MAVS antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the MAVS antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))
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别名
- MAVS
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背景
- Double-stranded RNA viruses are recognized in a cell type-dependent manner by the transmembrane receptor TLR3 or by the cytoplasmic RNA helicases MDA5 and RIGI. These interactions initiate signaling pathways that differ in their initial steps but converge in the activation of the protein kinases IKKA and IKKB which activate NFKB, or TBK1 and IKKE (IKBKE, MIM 605048), which activate IRF3. Activated IRF3 and NFKB induce transcription of IFNB. For the TLR3 pathway, the intermediary molecule before the pathways converge is the cytoplasmic protein TRIF. For RIGI, the intermediary protein is mitochondria-bound IPS1.
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UniProt
- Q7Z434
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途径
- Activation of Innate immune Response, Inositol Metabolic Process, Hepatitis C
抗原
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