MARCKS 抗体 (AA 241-271)
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Quick Overview for MARCKS 抗体 (AA 241-271) (ABIN3031923)
抗原
See all MARCKS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 241-271
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纯化方法
- Purified
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免疫原
- A portion of amino acids 241-271 from the human protein was used as the immunogen for this MARCKS antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the MARCKS antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the MARCKS antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- MARCKS (Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))
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别名
- MARCKS
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背景
- MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.
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UniProt
- P29966
抗原
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