LOXL3 抗体 (AA 715-744)
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Quick Overview for LOXL3 抗体 (AA 715-744) (ABIN3031669)
抗原
See all LOXL3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 715-744
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交叉反应 (详细)
- Expected species reactivity: Mouse
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 715-744 from the human protein was used as the immunogen for this LOXL3 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the LOXL3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the LOXL3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- LOXL3 (Lysyl Oxidase-Like 3 (LOXL3))
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别名
- LOXL3
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背景
- This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Alternatively spliced transcript variants of this gene have been reported but their full-length nature has not been determined.
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UniProt
- P58215
抗原
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