Leptin Receptor 抗体 (AA 23-52)
Quick Overview for Leptin Receptor 抗体 (AA 23-52) (ABIN3031603)
抗原
See all Leptin Receptor (LEPR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 23-52
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纯化方法
- Purified
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免疫原
- A portion of amino acids 23-52 from the human protein was used as the immunogen for this Leptin Receptor antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the Leptin Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50,IHC (Paraffin): 1:50-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Leptin Receptor antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Leptin Receptor (LEPR)
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别名
- Leptin Receptor
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背景
- Leptin, an adipocyte-specific hormone, regulates adipose-tissue mass through hypothalamic effects on satiety and energy expenditure by acting through the leptin receptor (LEPR). LEPR is a single-transmembrane-domain receptor of the cytokine receptor family that is identical to the mouse diabetes (db) gene product. During weight loss, leptin levels decrease, whereas soluble LEPR levels and the receptor bound fraction of leptin increases. The presence of LEPR in the absorptive cells of the small intestine suggests that leptin may have a physiological role in the regulation of nutrient absorption.
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UniProt
- P48357
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途径
- JAK/STAT Signaling, AMPK Signaling, Feeding Behaviour
抗原
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