LDLR 抗体 (AA 391-419)
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Quick Overview for LDLR 抗体 (AA 391-419) (ABIN3031637)
抗原
See all LDLR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 391-419
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交叉反应 (详细)
- Expected species reactivity: Rat, Pig, Rabbit, Hamster, Xenopus
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 391-419 from the human protein was used as the immunogen for this LDLR antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the LDLR antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the LDLR antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- LDLR (Low Density Lipoprotein Receptor (LDLR))
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别名
- LDLR
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背景
- The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place.
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UniProt
- P01130
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途径
- Hepatitis C, Lipid Metabolism
抗原
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