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LCK 抗体 (AA 23-52)

Name: LCK 抗体 (AA 23-52)
SKU: ABIN3031644
Availability: OutOfStock

This anti-LCK antibody is a 兔多克隆 antibody detecting LCK in WB, ELISA, IHC, IF 和 FACS. Suitable for 人, 小鼠和大鼠.

Western blot analysis of lysate from 1) mouse thymus and 2) rat thymus tissue lysate using LCK antibody at 1:1000. (LCK 抗体 (AA 23-52))

Confocal immunofluorescent analysis of LCK antibody with A2058 cells followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (LCK 抗体 (AA 23-52))

IHC analysis of FFPE human breast carcinoma tissue stained with the LCK antibody (LCK 抗体 (AA 23-52))

IHC

LCK antibody flow cytometric analysis of A2058 cells (green) compared to a negative control (blue). (LCK 抗体 (AA 23-52))

FACS

6 images

产品编号 ABIN3031644

发货至: 中国

Quick Overview for LCK 抗体 (AA 23-52) (ABIN3031644)

抗原

See all LCK 抗体

LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This LCK antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Discover our top product LCK Primary Antibody

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AA 23-52

纯化方法

Antigen affinity purified

免疫原

A portion of amino acids 23-52 from the human protein was used as the immunogen for this LCK antibody.

亚型

Ig Fraction
anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 1-240) antibody
LCK 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 1-539) antibody
LCK 适用: 人 WB, ELISA, IP, RNAi 宿主: 小鼠 Monoclonal 3F7-F5 unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 22-36) antibody
LCK 适用: 人 WB, IP, ICC, ICFC 宿主: 小鼠 Monoclonal LCK-01 unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 1-539) antibody
LCK 适用: 人 ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 468-506), (C-Term) antibody
LCK 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 480-509) antibody
LCK 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 421-509) antibody
LCK 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 39-52) antibody
Verified LCK 适用: 人, 大鼠, Pig WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (pTyr505) antibody
LCK 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 1-539) antibody
LCK 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

应用备注

Titration of the LCK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50

限制

仅限研究用
状态

Liquid

缓冲液

In 1X PBS, pH 7.4, with 0.09 % sodium azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Aliquot the LCK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
抗原

LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))

别名

LCK

背景

LSK, which belongs to the SRC subfamily of Tyr protein kinases, may participate in antigen-induced T-cell activation. It binds to phosphatidylinositol 3'-kinase (PI3K) from T lymphocytes through its SH3 domain and to the tyrosine phosphorylated form of KHDRBS1/p70 through its SH2 domain. LSK is bound to the cytoplasmic domain of either CD4 or CD8. This protein is involved in leukemias by a chromosomal translocation t(1,7)(p34,q34) which involves LCK and T-cell receptor beta chain (TCRB) genes.

UniProt

P06239

途径

TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling