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L1CAM 抗体 (AA 1154-1182)

L1CAM 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3031578
发货至: 中国
  • 抗原 See all L1CAM 抗体
    L1CAM (L1 Cell Adhesion Molecule (L1CAM))
    抗原表位
    • 16
    • 10
    • 8
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1154-1182
    适用
    • 97
    • 37
    • 31
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 76
    • 24
    • 2
    克隆类型
    • 66
    • 35
    • 1
    多克隆
    标记
    • 46
    • 11
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This L1CAM antibody is un-conjugated
    应用范围
    • 50
    • 39
    • 32
    • 22
    • 19
    • 14
    • 13
    • 8
    • 8
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA
    交叉反应 (详细)
    Expected species reactivity: Rat
    纯化方法
    Antigen affinity purified
    免疫原
    A portion of amino acids 1154-1182 from the human protein was used as the immunogen for this L1CAM antibody.
    亚型
    Ig Fraction
    Top Product
    Discover our top product L1CAM Primary Antibody
  • 应用备注
    Titration of the L1CAM antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    1. Cleavage by ADAM10 results in 180 and 40 kDa bands while cleavage by Plasmin results in 140 and 80 kDa bands.\. Western blot: 1:1000 (1)

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the L1CAM antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    L1CAM (L1 Cell Adhesion Molecule (L1CAM))
    别名
    L1CAM (L1CAM 产品)
    别名
    l1cam-a antibody, CAML1 antibody, CD171 antibody, HSAS antibody, HSAS1 antibody, MASA antibody, MIC5 antibody, N-CAM-L1 antibody, N-CAML1 antibody, NCAM-L1 antibody, S10 antibody, SPG1 antibody, L1 antibody, Hsas antibody, Hyd antibody, NCAML1 antibody, L1 cell adhesion molecule S homeolog antibody, L1 cell adhesion molecule antibody, l1cam.S antibody, L1CAM antibody, L1cam antibody
    背景
    L1CAM is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant.
    UniProt
    P32004
    途径
    Synaptic Membrane
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