L1CAM 抗体 (AA 1154-1182)
Quick Overview for L1CAM 抗体 (AA 1154-1182) (ABIN3031578)
抗原
See all L1CAM 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1154-1182
-
交叉反应 （详细）
- Expected species reactivity: Rat
-
纯化方法
- Antigen affinity purified
-
免疫原
- A portion of amino acids 1154-1182 from the human protein was used as the immunogen for this L1CAM antibody.
-
亚型
- Ig Fraction
-
-
anti-L1 Cell Adhesion Molecule (L1CAM) (AA 151-200) antibody
L1CAM 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) antibodyL1CAM 适用: 人, 犬, 猴 WB, FACS, IF 宿主: 小鼠 Monoclonal 2G9 unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) antibodyL1CAM 适用: 人, 猴 WB, FACS 宿主: 小鼠 Monoclonal 2A5 unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) (AA 1143-1257) antibodyL1CAM 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) (AA 20-197) antibodyL1CAM 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 5C6A10 unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) (AA 526-690) antibodyL1CAM 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) (AA 995-1119) antibodyL1CAM 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) (AA 1101-1257) antibodyL1CAM 适用: 人, 大鼠 FACS, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) antibodyL1CAM 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) (AA 20-1120) antibodyL1CAM 适用: 人 FACS, ELISA 宿主: 兔 Monoclonal DM155 unconjugated
-
-
应用备注
-
Titration of the L1CAM antibody may be required due to differences in protocols and secondary/substrate sensitivity.
1. Cleavage by ADAM10 results in 180 and 40 kDa bands while cleavage by Plasmin results in 140 and 80 kDa bands.\. Western blot: 1:1000 (1)
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the L1CAM antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- L1CAM (L1 Cell Adhesion Molecule (L1CAM))
-
别名
- L1CAM
-
背景
- L1CAM is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant.
-
UniProt
- P32004
-
途径
- Synaptic Membrane
抗原
-
