L1CAM 抗体 (AA 1154-1182)
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北京 101111
Quick Overview for L1CAM 抗体 (AA 1154-1182) (ABIN3031578)
抗原
See all L1CAM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1154-1182
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交叉反应 （详细）
- Expected species reactivity: Rat
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 1154-1182 from the human protein was used as the immunogen for this L1CAM antibody.
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亚型
- Ig Fraction
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anti-L1 Cell Adhesion Molecule (L1CAM) antibody
L1CAM 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) (AA 1143-1257) antibodyL1CAM 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) antibodyL1CAM 适用: 人, 犬, 猴 WB, FACS, IF 宿主: 小鼠 Monoclonal 2G9 unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) antibodyL1CAM 适用: 人, 猴 WB, FACS 宿主: 小鼠 Monoclonal 2A5 unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) (AA 20-197) antibodyL1CAM 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 5C6A10 unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) (AA 653-667), (Extracellular) antibodyL1CAM 适用: 人 WB, IHC, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) (AA 526-690) antibodyL1CAM 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) (AA 995-1119) antibodyL1CAM 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) antibodyKD Validated L1CAM 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB560 unconjugated Recombinant Antibody
anti-L1 Cell Adhesion Molecule (L1CAM) antibodyKD Validated L1CAM 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 25GB3690 unconjugated
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应用备注
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Titration of the L1CAM antibody may be required due to differences in protocols and secondary/substrate sensitivity.
1. Cleavage by ADAM10 results in 180 and 40 kDa bands while cleavage by Plasmin results in 140 and 80 kDa bands.\. Western blot: 1:1000 (1)
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the L1CAM antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- L1CAM (L1 Cell Adhesion Molecule (L1CAM))
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别名
- L1CAM
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背景
- L1CAM is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant.
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UniProt
- P32004
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途径
- Synaptic Membrane
抗原
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