JMJD4 抗体 (AA 1-30)
Our Local Distributor
北京 101111
Quick Overview for JMJD4 抗体 (AA 1-30) (ABIN3031514)
抗原
适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-30
-
纯化方法
- Purified
-
免疫原
- A portion of amino acids 1-30 from the human protein was used as the immunogen for this JMJD4 antibody.
-
亚型
- Ig Fraction
-
-
anti-Jumonji Domain Containing 4 (JMJD4) (AA 72-121) antibody
JMJD4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Jumonji Domain Containing 4 (JMJD4) (C-Term) antibodyJMJD4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Jumonji Domain Containing 4 (JMJD4) (AA 423-455), (C-Term) antibodyJMJD4 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB10802 unconjugated
anti-Jumonji Domain Containing 4 (JMJD4) (C-Term) antibodyJMJD4 适用: 人, 小鼠, 大鼠, Pig, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Jumonji Domain Containing 4 (JMJD4) (N-Term) antibodyJMJD4 适用: 人, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Jumonji Domain Containing 4 (JMJD4) (C-Term) antibodyJMJD4 适用: 人, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Titration of the JMJD4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the JMJD4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- JMJD4 (Jumonji Domain Containing 4 (JMJD4))
-
别名
- JMJD4
-
背景
- Covalent modification of histones plays critical role in regulating chromatin structure and transcription. While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones. A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function. Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate. Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9). Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.
-
UniProt
- Q9H9V9
抗原
-
