IRF8 抗体 (AA 241-269)
Quick Overview for IRF8 抗体 (AA 241-269) (ABIN3031425)
抗原
See all IRF8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 241-269
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纯化方法
- Purified
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免疫原
- A portion of amino acids 241-269 from the human protein was used as the immunogen for this IRF8 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the IRF8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the IRF8 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- IRF8 (Interferon Regulatory Factor 8 (IRF8))
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别名
- IRF8
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背景
- Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection.
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UniProt
- Q02556
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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