IRF4 抗体 (AA 164-191)
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Quick Overview for IRF4 抗体 (AA 164-191) (ABIN3031420)
抗原
See all IRF4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 164-191
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纯化方法
- Purified
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免疫原
- A portion of amino acids 164-191 from the human protein was used as the immunogen for this IRF4 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the IRF4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the IRF4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- IRF4 (Interferon Regulatory Factor 4 (IRF4))
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别名
- IRF4
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背景
- The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6,14)(p25,q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.
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UniProt
- Q15306
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途径
- Chromatin Binding
抗原
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