ITGA7 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for ITGA7 抗体 (C-Term) (ABIN3031401)
抗原
See all ITGA7 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
纯化方法
- Antigen affinity purified
-
免疫原
- This Integrin alpha 7 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 1149-1181 amino acids from the C-terminal region of human ITGA7.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- Titration of the Integrin alpha 7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:2000-8000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the Integrin alpha 7 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- ITGA7 (Integrin, alpha 7 (ITGA7))
-
别名
- Integrin alpha 7
-
背景
- Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers. During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro). Acts as Schwann cell receptor for laminin-2. Acts as a receptor of COMP and mediates its effect on vascular smooth muscle cells (VSMCs) maturation (By similarity). Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells.
-
UniProt
- Q13683
-
途径
- Integrin Complex
抗原
-