IGHM 抗体 (AA 103-131)
Quick Overview for IGHM 抗体 (AA 103-131) (ABIN3031293)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 103-131
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纯化方法
- Purified
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免疫原
- A portion of amino acids 103-131 from the human protein was used as the immunogen for this IGHM antibody.
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亚型
- Ig Fraction
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anti-Immunoglobulin Heavy Constant mu (IGHM) (AA 310-452) antibody
IGHM 适用: 人 IHC, WB, FACS, ELISA 宿主: 小鼠 Monoclonal 8B9D3 unconjugated
anti-Immunoglobulin Heavy Constant mu (IGHM) antibodyIGHM 适用: 人 IHC, WB 宿主: 兔 Monoclonal unconjugated
anti-Immunoglobulin Heavy Constant mu (IGHM) antibodyIGHM 适用: 人 IHC, StM, ISt 宿主: 兔 Monoclonal IGHM-3776R unconjugated Recombinant Antibody
anti-Immunoglobulin Heavy Constant mu (IGHM) antibodyIGHM 适用: 人 IHC, WB, StM, FACS, IF 宿主: 小鼠 Monoclonal IM373 unconjugated
anti-Immunoglobulin Heavy Constant mu (IGHM) (AA 45-178) antibodyIGHM 适用: 人 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Immunoglobulin Heavy Constant mu (IGHM) (AA 1-489) antibodyIGHM 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Immunoglobulin Heavy Constant mu (IGHM) antibodyIGHM 适用: 人 IHC, StM 宿主: 兔 Monoclonal IGHM-3135R unconjugated Recombinant Antibody
anti-Immunoglobulin Heavy Constant mu (IGHM) antibodyIGHM 适用: 人 IHC, StM, FACS, IF, ELISA, Coat 宿主: 小鼠 Monoclonal rIGHM-1623 unconjugated Recombinant Antibody
anti-Immunoglobulin Heavy Constant mu (IGHM) antibodyIGHM 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal rIM373 unconjugated Recombinant Antibody
anti-Immunoglobulin Heavy Constant mu (IGHM) (AA 391-440) antibodyIGHM 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Titration of the IGHM antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the IGHM antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- IGHM (Immunoglobulin Heavy Constant mu (IGHM))
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别名
- IGHM
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背景
- IgM antibodies play an important role in primary defense mechanisms. They have been shown to be involved in early recognition of external invaders like bacteria and viruses, cellular waste and modified self, as well as in recognition and elimination of precancerous and cancerous lesions. The membrane-bound form is found in the majority of normal B-cells alongside with IgD. Membrane-bound IgM induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases. It may cause death of cells by apoptosis. It is also found in soluble form, which represents about 30 % of the total serum immunoglobulins where it is found almost exclusively as a homopentamer. After the antigen binds to the B-cell receptor, the secreted form is secreted in large amounts. [UniProt]
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UniProt
- P01871
抗原
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