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IDH1 抗体 (AA 116-143)

This anti-IDH1 antibody is a 兔 多克隆 antibody detecting IDH1 in WB, IHC, ELISA, FACS 和 IF. Suitable for 人 和 小鼠.
产品编号 ABIN3031506
发货至: 中国

Quick Overview for IDH1 抗体 (AA 116-143) (ABIN3031506)

抗原

See all IDH1 抗体
IDH1 (Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1))

适用

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人, 小鼠

宿主

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克隆类型

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  • 70
多克隆

标记

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This IDH1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)
  • 抗原表位

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    AA 116-143

    交叉反应 (详细)

    Expected species reactivity: Rat, Bovine

    纯化方法

    Purified

    免疫原

    A portion of amino acids 116-143 from the human protein was used as the immunogen for this IDH1 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the IDH1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the IDH1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    IDH1 (Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1))

    别名

    IDH1

    背景

    IDH1 belongs to two distinct subclasses. The protein is the NADP(+)-dependent Isocitrate Dehydrogenase found in the cytoplasm and peroxisomes. This protein contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. [Wiki]

    UniProt

    O75874

    途径

    Warburg Effect
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