HIF1A 抗体 (AA 728-757)
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北京 101111
Quick Overview for HIF1A 抗体 (AA 728-757) (ABIN3031282)
抗原
See all HIF1A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 728-757
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纯化方法
- Purified
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免疫原
- A portion of amino acids 728-757 from the human protein was used as the immunogen for this HIF-1 alpha antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the HIF-1 alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,IHC (Paraffin): 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the HIF-1 alpha antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- HIF1A (Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A))
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别名
- HIF-1 alpha
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背景
- Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT).
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UniProt
- Q16665
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途径
- Positive Regulation of Peptide Hormone Secretion, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Transition Metal Ion Homeostasis, Tube Formation, Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals, Warburg Effect
抗原
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