HDAC3 抗体 (AA 383-412)
Our Local Distributor
北京 101111
Quick Overview for HDAC3 抗体 (AA 383-412) (ABIN3031229)
抗原
See all HDAC3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 383-412
-
交叉反应 (详细)
- Expected species reactivity: Mouse, Rat
-
纯化方法
- Antigen affinity purified
-
免疫原
- A portion of amino acids 383-412 from the human protein was used as the immunogen for this HDAC3 antibody.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- Titration of the HDAC3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the HDAC3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- HDAC3 (Histone Deacetylase 3 (HDAC3))
-
别名
- HDAC3
-
背景
- Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq].
-
UniProt
- O15379
-
途径
- Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
-