Glypican 3 抗体 (AA 529-560)
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- 抗原 See all Glypican 3 (GPC3) 抗体
- Glypican 3 (GPC3)
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抗原表位
- AA 529-560
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Glypican 3 antibody is un-conjugated
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应用范围
- Immunofluorescence (IF), Western Blotting (WB), ELISA
- 纯化方法
- Purified
- 免疫原
- A portion of amino acids 529-560 from the human protein was used as the immunogen for this GPC3 antibody.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product GPC3 Primary Antibody
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- 应用备注
- Titration of the GPC3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:10-1:50,Western blot: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Aliquot the GPC3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- 抗原
- Glypican 3 (GPC3)
- 别名
- GPC3 (GPC3 产品)
- 背景
- GPC3 is a cell surface proteoglycan that bears heparan sulfate. This protein may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. Members of the glypican-related integral membrane proteoglycan family contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol (GPI) linkage. These proteins may play a role in the control of cell division, growth regulation, and tumor predisposition. Deletion mutations in GPC3 are the cause of Simpson-Golabi-Behmel syndrome (SGBS), also known as Simpson dysmorphia syndrome (SDYS). SGBS is a condition characterized by pre- and postnatal overgrowth (gigantism) with visceral and skeletal anomalies.
- UniProt
- P51654
- 途径
- Glycosaminoglycan Metabolic Process
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