GFAP 抗体 (N-Term)
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Quick Overview for GFAP 抗体 (N-Term) (ABIN3028680)
抗原
See all GFAP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-36, N-Term
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原理
- Zebrafish Gfap Antibody
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纯化方法
- Antigen affinity
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免疫原
- This Gfap antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 2-36 amino acids from the N-terminal region of zebrafish Gfap.
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亚型
- Ig Fraction
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anti-Glial Fibrillary Acidic Protein (GFAP) (AA 51-150) antibody
GFAP 适用: 人, 大鼠, 小鼠 WB, ELISA, ICC, FACS, IHC (p), IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Glial Fibrillary Acidic Protein (GFAP) (C-Term) antibodyGFAP 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glial Fibrillary Acidic Protein (GFAP) (AA 93-432) antibodyGFAP 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glial Fibrillary Acidic Protein (GFAP) (AA 1-430) antibodyGFAP 适用: 大鼠 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Glial Fibrillary Acidic Protein (GFAP) (AA 253-354) antibodyGFAP 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Glial Fibrillary Acidic Protein (GFAP) (C-Term) antibodyVerified GFAP 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Glial Fibrillary Acidic Protein (GFAP) (pSer38) antibodyGFAP 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glial Fibrillary Acidic Protein (GFAP) (AA 292-432) antibodyGFAP 适用: 人 WB, IHC, IF, ELISA, FACS 宿主: 小鼠 Monoclonal 1C91F1 unconjugated
anti-Glial Fibrillary Acidic Protein (GFAP) antibodyGFAP 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 小鼠 Monoclonal unconjugated
anti-Glial Fibrillary Acidic Protein (GFAP) (AA 108-211) antibodyGFAP 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Titration of the Gfap antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Gfap antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- GFAP (Glial Fibrillary Acidic Protein (GFAP))
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别名
- Gfap
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背景
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Glial fibrillary acidic protein (GFAP) is a major intermediate filament protein expressed in astroglial cells and radial glia of the central nervous system (CNS). In zebrafish (Danio rerio), GFAP serves as a key structural and functional component of glial cells, particularly radial glial progenitors, which play essential roles in CNS development, neurogenesis, and regeneration.
Zebrafish GFAP shares significant structural and functional homology with mammalian GFAP, including a conserved α-helical rod domain crucial for filament assembly. It is prominently expressed during embryonic development and persists in specific glial populations in the adult brain and spinal cord. Unlike in mammals, radial glia expressing GFAP remain active as neural stem cells in the adult zebrafish CNS, making GFAP an important marker for studying neurodevelopment and regeneration.
GFAP expression in zebrafish is widely used as a glial cell marker in developmental biology, neural stem cell research, and models of CNS injury and repair. Its upregulation is also indicative of reactive gliosis following CNS trauma.
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UniProt
- Q58EE9
抗原
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