GAK 抗体 (AA 15-45)
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北京 101111
Quick Overview for GAK 抗体 (AA 15-45) (ABIN3030600)
抗原
See all GAK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 15-45
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交叉反应 (详细)
- Expected species reactivity: Rat
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纯化方法
- Purified
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免疫原
- A portion of amino acids 15-45 from the human protein was used as the immunogen for this GAK antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the GAK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:50-1:100,Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the GAK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- GAK (Cyclin G Associated Kinase (GAK))
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别名
- GAK
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背景
- GAK, a member of the Ser/Thr protein kinase family, associates with cyclin G and CDK5. It appears to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1. GAK localizes to the perinuclear area and to the trans-Golgi network. It is also observed on the plasma membrane, probably at focals adhesions. Expression is ubiquitous, wiht highest levels in testis. The protein contains 1 J domain and 1 tensin domain.
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UniProt
- Q6P490
抗原
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