Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
交叉反应 (详细)
Expected species reactivity: Rat, Bovine
纯化方法
Antigen affinity purified
免疫原
A portion of amino acids 199-235 from the human protein was used as the immunogen for this ERAB antibody.
亚型
Ig Fraction
应用备注
Titration of the ERAB antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
限制
仅限研究用
状态
Liquid
缓冲液
In 1X PBS pH 7.4 with 0.09 % sodium azide
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Aliquot the ERAB antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
抗原
Endoplasmic Reticulum Amyloid Binding Protein (ERAB)
背景
Endoplasmic Reticulum Amyloid Binding protein is a member of the family of short chain dehydrogenase/reductases, unique among this family, it binds amyloid b-peptide and exhibits enzymatic activity toward a wide variety of substrates including linear alcohols. In an amyloid beta-abundant environment, ERAB appears to trigger cell stress induced by the amyloid peptide.