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Endothelin 3 抗体 (AA 168-197)

This anti-Endothelin 3 antibody is a 兔 多克隆 antibody detecting Endothelin 3 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN3030805
发货至: 中国

Quick Overview for Endothelin 3 抗体 (AA 168-197) (ABIN3030805)

抗原

See all Endothelin 3 (EDN3) 抗体
Endothelin 3 (EDN3)

适用

  • 30
  • 4
  • 2
  • 2
  • 1
  • 1

宿主

  • 31
  • 3

克隆类型

  • 32
  • 2
多克隆

标记

  • 22
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Endothelin 3 antibody is un-conjugated

应用范围

  • 23
  • 12
  • 7
  • 5
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 7
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 168-197

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 168-197 from the human protein was used as the immunogen for this EDN3 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the EDN3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS pH 7.4 with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the EDN3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Endothelin 3 (EDN3)

    别名

    EDN3

    背景

    The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.

    UniProt

    P14138

    途径

    Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones
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