RCAN1 抗体 (AA 222-252)
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Quick Overview for RCAN1 抗体 (AA 222-252) (ABIN3032453)
抗原
See all RCAN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 222-252
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交叉反应 (详细)
- Expected species reactivity: Mouse, Rat, Bovine, Hamster
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纯化方法
- Purified
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免疫原
- A portion of amino acids 222-252 from the human protein was used as the immunogen for this DSCR1 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the DSCR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the DSCR1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- RCAN1 (Regulator of Calcineurin 1 (RCAN1))
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别名
- DSCR1
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背景
- DSCR1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. The gene for this protein is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of DSCR1 may lead to neurofibrillary tangles such as those associated with Alzheimer disease.
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UniProt
- P53805
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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