DR1 抗体 (AA 83-112)
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Quick Overview for DR1 抗体 (AA 83-112) (ABIN3029101)
抗原
See all DR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 83-112
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交叉反应 (详细)
- Expected species reactivity: Rat, Chicken
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 83-112 from the human protein was used as the immunogen for this DR1 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the DR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the DR1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- DR1 (TATA-Binding Protein-Associated Phosphoprotein (DR1))
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别名
- DR1 (Down-Regulator of Transcription 1)
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背景
- This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription.
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UniProt
- Q01658
抗原
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