DNMT3A 抗体 (AA 723-752)
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Quick Overview for DNMT3A 抗体 (AA 723-752) (ABIN3030749)
抗原
See all DNMT3A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 723-752
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交叉反应 (详细)
- Expected species reactivity: Mouse, Rat
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纯化方法
- Purified
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免疫原
- A portion of amino acids 723-752 from the human protein was used as the immunogen for this Dnmt3a antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the Dnmt3a antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Dnmt3a antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))
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别名
- Dnmt3a
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背景
- CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. Dnmt3a is a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.
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UniProt
- Q9Y6K1
抗原
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