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Doublecortin 抗体 (AA 107-137)

This anti-Doublecortin antibody is a 兔 多克隆 antibody detecting Doublecortin in WB, ELISA 和 IHC. Suitable for 人.
产品编号 ABIN3030770
发货至: 中国

Quick Overview for Doublecortin 抗体 (AA 107-137) (ABIN3030770)

抗原

See all Doublecortin (DCX) 抗体
Doublecortin (DCX)

适用

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宿主

  • 94
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克隆类型

  • 91
  • 22
多克隆

标记

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This Doublecortin antibody is un-conjugated

应用范围

  • 81
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 7
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    AA 107-137

    交叉反应 (详细)

    Expected species reactivity: Mouse, Rat

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 107-137 from the human protein was used as the immunogen for this DCX antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the DCX antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the DCX antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Doublecortin (DCX)

    别名

    DCX

    背景

    In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. DCX is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. It contains two doublecortin domains, which bind microtubules. In addition, this protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in the gene encoding DCX are a cause of X-linked lissencephaly.

    UniProt

    O43602
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