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CPT1C 抗体 (AA 752-782)

This anti-CPT1C antibody is a 兔 多克隆 antibody detecting CPT1C in WB, ELISA 和 FACS. Suitable for 人.
产品编号 ABIN3030283
发货至: 中国

Quick Overview for CPT1C 抗体 (AA 752-782) (ABIN3030283)

抗原

See all CPT1C 抗体
CPT1C (Carnitine Palmitoyltransferase 1C (CPT1C))

适用

  • 50
  • 6
  • 3

宿主

  • 51
  • 1
  • 1

克隆类型

  • 52
  • 1
多克隆

标记

  • 21
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CPT1C antibody is un-conjugated

应用范围

  • 38
  • 27
  • 13
  • 13
  • 8
  • 7
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 752-782

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 752-782 from the human protein was used as the immunogen for this CPT1C antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the CPT1C antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the CPT1C antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    CPT1C (Carnitine Palmitoyltransferase 1C (CPT1C))

    别名

    CPT1C

    背景

    The Cpt1 family of proteins are outer mitochondrial membrane proteins that regulate the entry into, and oxidation of fatty acids by, mitochondria. Malonyl-CoA, an intermediate in fatty acid synthesis, has been implicated as a regulatory component of the energy sensing system that feeds into hypothalmic neurons to impart energy homeostasis. Malonyl-CoA levels in the hypothalamus are dynamically regulated by fasting and feeding, altering subsequent feeding behaviour. Cpt1c, the brain-specific carnitine O-palmitoyltransferase 1, is thought to relay information about malonyl-CoA levels in hypothalamic neurons that express orexigenic and anorexigenic neuropeptides that regulate food intake and peripheral energy expenditure. Unlike other Cpt1 proteins, Cpt1c binds Malonyl-CoA but does not catalyse the transfer of the malonyl group from CoA to carnitine.

    UniProt

    Q8TCG5

    途径

    AMPK Signaling, Monocarboxylic Acid Catabolic Process
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