CDK1 抗体 (AA 213-241)
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Quick Overview for CDK1 抗体 (AA 213-241) (ABIN3030601)
抗原
See all CDK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 213-241
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交叉反应 (详细)
- Expected species reactivity: Mouse, Rat, Xenopus
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 213-241 from the human protein was used as the immunogen for this CDC2 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the CDC2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the CDC2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- CDK1 (Cyclin-Dependent Kinase 1 (CDK1))
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别名
- CDC2
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背景
- CDC2 is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of CDC2 is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.
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UniProt
- P06493
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途径
- Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA
抗原
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