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CD86 抗体 (AA 269-298)

This anti-CD86 antibody is a 兔 多克隆 antibody detecting CD86 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN3030429
发货至: 中国

Quick Overview for CD86 抗体 (AA 269-298) (ABIN3030429)

抗原

See all CD86 抗体
CD86

适用

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宿主

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克隆类型

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多克隆

标记

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This CD86 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 269-298

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 269-298 from the human protein was used as the immunogen for this CD86 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the CD86 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the CD86 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    CD86

    别名

    CD86

    背景

    This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined. [provided by RefSeq].

    UniProt

    P42081

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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