CD86 抗体 (AA 269-298)
Quick Overview for CD86 抗体 (AA 269-298) (ABIN3030429)
抗原
See all CD86 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 269-298
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 269-298 from the human protein was used as the immunogen for this CD86 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the CD86 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the CD86 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- CD86
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别名
- CD86
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背景
- This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined. [provided by RefSeq].
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UniProt
- P42081
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
抗原
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