CD43 抗体 (AA 230-257)
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北京 101111
Quick Overview for CD43 抗体 (AA 230-257) (ABIN3032562)
抗原
See all CD43 (SPN) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 230-257
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纯化方法
- Purified
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免疫原
- A portion of amino acids 230-257 from the human protein was used as the immunogen for this CD43 antibody.
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亚型
- IgM
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应用备注
- Titration of the CD43 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100-1:250
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the CD43 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- CD43 (SPN) (Sialophorin (SPN))
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别名
- CD43
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背景
- One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1. During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response (By similarity) [UniProt]
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UniProt
- P16150
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途径
- Regulation of Leukocyte Mediated Immunity
抗原
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