CD1e 抗体 (AA 184-212)
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Quick Overview for CD1e 抗体 (AA 184-212) (ABIN3030538)
抗原
See all CD1e 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 184-212
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 184-212 from the human protein was used as the immunogen for this CD1e antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the CD1e antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50,Immunofluorescence: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the CD1e antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- CD1e
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别名
- CD1e
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背景
- CD1E encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes within Golgi compartments, endosomes, and lysosomes, and is cleaved into a stable soluble form. The soluble form is required for the intracellular processing of some glycolipids into a form that can be presented by other CD1 family members.
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UniProt
- P15812
抗原
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