CCR10 抗体 (AA 1-30)
Our Local Distributor
北京 101111
Quick Overview for CCR10 抗体 (AA 1-30) (ABIN3030489)
抗原
See all CCR10 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-30
-
纯化方法
- Antigen affinity purified
-
免疫原
- A portion of amino acids 1-30 from the human protein was used as the immunogen for this CCR10 antibody.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- Titration of the CCR10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the CCR10 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- CCR10 (Chemokine (C-C Motif) Receptor 10 (CCR10))
-
别名
- CCR10
-
背景
- Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues, the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27, MIM 604833), CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).
-
UniProt
- P46092
抗原
-