CCR1 抗体 (AA 1-30)
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Quick Overview for CCR1 抗体 (AA 1-30) (ABIN3030216)
抗原
See all CCR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-30
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 1-30 from the human protein was used as the immunogen for this CCR1 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the CCR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the CCR1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))
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别名
- CCR1
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背景
- CCR1 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p.
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UniProt
- P32246
抗原
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