CA9 抗体 (AA 63-90)
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Quick Overview for CA9 抗体 (AA 63-90) (ABIN3030277)
抗原
See all CA9 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 63-90
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纯化方法
- Purified
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免疫原
- A portion of amino acids 63-90 from the human protein was used as the immunogen for this CA9 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the CA9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the CA9 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- CA9 (Carbonic Anhydrase IX (CA9))
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别名
- CA9
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背景
- Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12. [Wiki]
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UniProt
- Q16790
抗原
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