BMP4 抗体 (AA 5-34)
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Quick Overview for BMP4 抗体 (AA 5-34) (ABIN3030177)
抗原
See all BMP4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 5-34
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交叉反应 (详细)
- Expected species reactivity: Mouse, Bovine, Rabbit
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纯化方法
- Purified
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免疫原
- A portion of amino acids 5-34 from the human protein was used as the immunogen for this BMP4 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the BMP4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the BMP4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- BMP4 (Bone Morphogenetic Protein 4 (BMP4))
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别名
- BMP4
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背景
- Bmp4 is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.
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UniProt
- P12644
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途径
- Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
抗原
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